A Postdoctoral position on mechanisms of ion channel clustering is open in the MV lab at the University of Washington, School of Medicine in Seattle, WA, USA. We study neuronal excitability, ion channels, and cellular signaling. Recent projects from our lab have focused on characterizing ion channel clustering in diverse cell types, including neurons and pacemaker cells. Ongoing projects are seeking to understand the physiological relevance of channel clusters in health and disease. Now, we have received significant funding to investigate the mechanisms controlling ion channel clustering combining electrophysiology (including patch-clamp, single-channel, perforated-patch), advanced microscopy (including FRET, TIRF, FRAP, super-resolution), and molecular techniques. This scientific program needs a driver able and willing to lead it. This position will be supported by our NIH/MIRA grant. Appropriate candidates will be energetic, curious, motivated, and collaborative and will already be familiar with a few of the techniques listed.
We are a supportive and multicultural laboratory that values and thrives in diversity. We invite and encourage applications from women, people of color, and people of diverse backgrounds, origins, sexual orientation, or gender. As mentors, we are committed to enhancing your postdoctoral experience by providing advanced training and offering opportunities for career development such as the programs Hit the Ground Running, Biomedical Research Integrity, Future Faculty Fellows, and the Postdoctoral Seminar Series.
Please send a personal statement expressing why you are interested in this position and how it would fit your training and career goals. In addition, attach CV (or Biosketch), and provide a list of three names and emails of references. Send your application to Oscar Vivas vivas@uw.edu or Claudia Moreno morenocm@uw.edu.
Illustrative references are:
- Moreno CM,Dixon RE, Tajada S, Yuan C, Opitz-Araya X, Binder MD, Santana LF. Ca(2+) entry into neurons is facilitated by cooperative gating of clustered CaV1.3 channels. Elife. 2016.
- Vivas O,Moreno CM, Santana LF, Hille B. Proximal clustering between BK and CaV1.3 channels promotes functional coupling and BK channel activation at low voltage. Elife. 2017.
Oscar Vivas
Research Assistant Professor
University of Washington
Department of Physiology and Biophysics
School of Medicine
1750 NE Pacific St.
Seattle, WA, 98195